There is no universally “best” CD-Screen format. Choose according to analyte chemistry, derivative charge, required selectivity, method goals, sample matrix, detector and instrument capability.
CD-Screen 5 µm, 250 × 4 mm
A conventional longer analytical format. It can be a logical starting point when an established workflow calls for a 250 mm column or when the method-development strategy benefits from the longer bed.
CD-Screen 3 µm, 150 × 4 mm
A shorter 150 mm column using smaller 3 µm particles. It may be considered when balancing efficiency and analysis time, provided the instrument can accommodate the resulting pressure requirements of the developed method.
CD-Screen-IEC
The dedicated portfolio option for ionic cyclodextrin derivatives. For SBECD and related ionic materials, this is the CD-Screen format to evaluate first.
Decision framework
| Question | Why it matters | Possible direction |
|---|---|---|
| Is the analyte/derivative ionic? | Charge can make the IEC selectivity relevant. | Consider CD-Screen-IEC. |
| Is an existing method built around a 250 mm format? | Method transfer may favour similar geometry. | Evaluate CDS-2504-05. |
| Is a shorter 150 mm bed desirable? | Can affect analysis time and efficiency trade-offs. | Evaluate CDS-1504-03. |
| What is the instrument pressure capability? | Smaller particles can increase pressure requirements. | Confirm system suitability before selection. |
| What detector and matrix are used? | They influence practical method conditions and sensitivity. | Share details for technical support. |
Information to send for selection help
- Target cyclodextrin or derivative
- Neutral or ionic material
- Sample matrix
- Current column and method, if any
- Detector
- Instrument model/pressure capability if relevant
- Required quantity and preferred dimensions